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Animal Residue Data Sheet - Cyfluthrin

Cyfluthrin, which includes beta-cyfluthrin is registered in Australia for use on Brassica vegetables, avocado, cereals, rape seed (canola), cotton, legume vegetables, pastures, pulses (chickpea, field peas, lupins, faba beans, navy beans-dried), alfalfa (lucerne), macadamia nuts, sorghum and tomatoes. Details of the registered use patterns can be found on the approved labels of registered products containing cyfluthrin and beta-cyfluthrin as the active constituent. This Animal Residue Data Sheet provides information on the possible residues in feed commodities obtained from crops treated with cyfluthrin, to provide assistance in the formulation of animal diets that should not result in the violation of animal commodity MRLs.

Current MRLs

The Australian MRLs for cyfluthrin in food and animal feed commodities listed in Table 1 and Table 4 of the MRL Standard [10 October 2002] are shown below. The residue definition of cyfluthrin and beta-cyfluthrin is cyfluthrin, sum of isomers.

Code Food MRL, mg/kg
Food Commodities
FI 0326 Avocado 0.1
VB 0040 Brassica (cole or cabbage) vegetables, Head cabbages,

Flowerhead brassicas

0.5
GC 0080 Cereal grains 2
SO 0691 Cotton seed 0.01
VP 0060 Legume vegetables 0.5
TN 0669 Macadamia nuts 0.05
VD 0070 Pulses 0.5
SO 0495 Rape seed *0.05
VO 0448 Tomato 0.2
CM 0654 Wheat bran, unprocessed 5
Animal commodities
MO 0105 Edible offal (mammalian) *0.01
PE 0112 Eggs *0.01
MF 0100 Mammalian fats (except milk fat) 0.5
MM 0095 Meat [mammalian] 0.02
ML 0106 Milks 0.1
PO 0111 Poultry, Edible offal of *0.01
PM 0110 Poultry meat [in the fat] *0.01
Animal feed commodities
Canola forage (green) 1
Canola fodder (dry) 2
Chick-pea forage (green) 5
Faba bean forage (green) 5
Field pea forage (green) 5
AF 0081 Forage of cereal grains 5
Grass pastures (green) 2
Legume pastures (except vetch) (green) 3
AL 0545 Lupin, forage (green) 2
Navy bean forage (green) and fodder 1
AF 0651 Sorghum forage (green) 0.5
AS 0081 Straw and fodder (dry) of cereal grains 5

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Summary of Maximum Feeding Levels and Livestock Dietary Intakes

The Maximum Feeding Level (MFL, the feeding level at which the MRLs are based), the equivalent Daily Dietary Intake For Livestock (DDIL) and the equivalent daily intake of cyfluthrin are summarised below.

Species MFL,
ppm in diet
Equivalent DDIL, mg/kg bw Equivalent intake of cyfluthrin,
mg/animal/day
Cattlea 5 0.23 80
Sheepb 5 0.21 12.5
Pigc 5 0.21 12.5
Poultryd 6 0.26 0.36
a Based on dairy cow animal feeding study
b Based on a 60 kg animal consuming 2.5 kg DM/day
c Based on a 60 kg animal consuming 2.5 kg DM/day
d Based on poultry feeding study

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Detailed Information

All Feed Commodities

Feed commodities that may contain residues of cyfluthrin are listed in the table below. The theoretical maximum proportion of the diet that the commodity can comprise, when residues are present at the MRL, without the significant risk of animal commodity MRLs being violated is also given. For instance, if wheat bran, unprocessed were fed to cattle at 80 % of the diet, the diet would need to be free of residues of cyfluthrin to minimise the risk of cattle commodity MRLs being violated. It should be noted that the feeding levels assumed by the APVMA when setting animal commodity MRLs are theoretical values, and they should not be taken as recommendations of appropriate rations for livestock.

Commodity a Assumed Maximum proportion of diet (%)b Feed intake (kg/animal/day)c MRL/ STMR
(mg/kg) d
Maximum intake of cyfluthrin from commodity (mg/animal/day)e Theoretical maximum proportion of diet (%)f
Cattle (Based on a 500 kg animal consuming 20 kg DM/day)
Cereal grains (excluding sorghum) 100 20 0.05 1 100
Sorghum 100 20 0.25 5 100
Cotton seed 30 6 0.01 0.06 100
Legume vegetables 100 20 0.5 10 100
Pulses 100 20 0.5 10 100
Rape seed 30 6 0.05 0.3 100
Wheat bran, unprocessed 40 8 5 40 80
Canola forage (green) 100 20 1 20 100
Canola fodder (dry) 100 20 2 40 100
Pulses forage (green) (includes chick-pea, faba bean, field pea) 100 20 2 † 40 100
Forage of cereal grains 100 20 0.29 5.8 100
Grass pastures (green) 100 20 2 40 100
Legume pastures (except vetch) (green) 100 20 0.87 17.4 100
Lupin, forage (green) 100 20 2 40 100
Navy bean forage (green) and fodder 100 20 1 20 100
Sorghum forage (green) 100 20 0.5 10 100
Straw and fodder (dry) of cereal grains 100 20 0.75 15 100
Sheep (Based on a 60 kg animal consuming 2.5 kg DM/day)
Cereal grains (excluding sorghum) 100 2.5 0.05 0.125 100
Sorghum 100 2.5 0.25 0.625 100
Cotton seed 30 0.75 0.01 0.0075 100
Legume vegetables 100 2.5 0.5 1.25 100
Pulses 100 2.5 0.5 1.25 100
Rape seed 30 0.75 *0.05 0.0375 100
Canola forage (green) 100 2.5 1 2.5 100
Canola fodder (dry) 100 2.5 2 5 100
Pulses forage (green) (includes chick-pea, faba bean, field pea) 100 2.5 2 † 5 100
Forage of cereal grains 100 2.5 0.29 0.725 100
Grass pastures (green) 100 2.5 2 5 100
Legume pastures (except vetch) (green) 100 2.5 0.87 2.175 100
Lupin, forage (green) 100 2.5 2 5 100
Navy bean forage (green) and fodder 100 2.5 1 2.5 100
Sorghum forage (green) 100 2.5 0.5 1.25 100
Straw and fodder (dry) of cereal grains 100 2.5 1.9 4.75 100
Pigs (Based on a 60 kg animal consuming 2.5 kg DM/day)
Cereal grains (excluding sorghum) 100 2.5 0.05 0.125 100
Sorghum 100 2.5 0.25 0.625 100
Cotton seed 30 0.75 0.01 0.0075 100
Legume vegetables 100 2.5 0.5 1.25 100
Pulses 100 2.5 0.5 1.25 100
Rape seed 30 0.75 *0.05 0.0375 100
Wheat bran, unprocessed 40 1.0 5 5 100
Poultry (Based on a 2 kg animal consuming 150 g DM/day)
Cereal grains (excluding sorghum) 100 0.15 0.05 0.0075 100
Sorghum 100 0.15 0.25 0.0375 100
Cotton seed 30 0.045 0.01 0.00045 100
Legume vegetables 100 0.15 0.5 0.075 100
Pulses 100 0.15 0.5 0.075 100
Rape seed 30 0.045 *0.05 0.00225 100
Wheat bran, unprocessed 20 0.03 5 0.15 48
a The feed commodities that may contain residues of cyfluthrin, and may form more than 20% of an animals diet.
b The maximum % of the diet that the commodity is assumed to comprise for the purposes of setting MRLs, based on Stockfeed Information Document 1
c The equivalent amount of feed for an animal of designated weight and feed intake that is assumed for the purposes of setting MRLs
d The MRL for each feed commodity (correction for dry weight basis where required)
e The maximum intake of cyfluthrin when the commodity is fed at the maximum assumed level (Column 1) in the absence of other sources of cyfluthrin.
f The maximum % of the diet at which the commodity could theoretically be fed without significant risk of exceeding animal commodity MRLs. It is assumed that the residue in the feed commodity is present at the MRL (or dry weight equivalent) and other dietary sources of cyfluthrin are absent.

† Due to a lack of residue data for all pulse forages, the highest level found (1.4 mg/kg) was rounded up to 2 mg/kg and included in the calculation.

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Abbreviations and Definitions

DM: Dry matter. The feed consumption for livestock and the residue levels in feed commodities are expressed on a dry matter basis.

DDIL: Daily Dietary Intake for Livestock. The level of dietary exposure for a specified chemical in a specified species that should not result in exceedance of the relevant animal commodity MRLs. Expressed in mg chemical/kg bodyweight.

MFL: Maximum Feeding Level. The level of dietary exposure for a specified chemical in a specified species that should not result in exceedance of the relevant animal commodity MRLs. Expressed in terms of ppm in the feed.

MRL: The concentration of a chemical residue, in units of mg/kg, that is legally permitted in or on a food or food commodity.

ppm in the feed: Parts per million in the feed. An alternate way of expressing the level of dietary exposure for a chemical. The level of chemical intake is calculated as though it were present uniformly in the total feed intake. The ppm in the feed is calculated using the following formula: DDIL (mg chemical/kg bw) _ body weight (kg) ¸ daily feed intake (kg).

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Attachment 1: Anticipated maximum dietary exposure

The following calculations outline the theoretical diet used to calculate the maximum anticipated dietary exposure, maximum feeding level (MFL) and the daily dietary intake for livestock (DDIL) for cattle, sheep, pigs and poultry.

Cattle

Feed group Feed commodity % in the diet Feed intake, kg/animal/daya MRL/ STMR, mg/kg % DMb Intake of cyfluthrin, mg/animal/dayc
Processed grain fraction Wheat bran, unprocessed 40 8 5   40
Fodder and Forage Canola, pulses, grass pastures, lupins, straw and fodder 60 12 2 - 24
Total   100 20     64
aBased on assumed feed consumption of 20 kg dry matter/day
bEstimate of percentage dry matter. Applied to MRLs expressed on a fresh weight basis
cBased on assumed bodyweight of 500 kg
Maximum anticipated dietary exposure: 64 mg/animal/day
Equivalent to: 0.128 mg/kg bw
Equivalent to: 3.2 ppm in the diet
MFL (Based on the available animal feeding data (Attachment 2): 5 ppm in the diet
Equivalent DDIL: 0.23 mg/kg bw

Sheep

Feed group Feed commodity % in the diet Feed intake, kg/animal/daya MRL, mg/kg % DMb Intake of cyfluthrin, mg/animal/dayc
Fodder and Forage Canola, pulses, grass pastures, lupins, straw and fodder 100 2.5 2 - 5
Total   100       5
aBased on assumed feed consumption of 2.5 kg dry matter/day
bEstimate of percentage dry matter. Applied to MRLs expressed on a fresh weight basis
cBased on assumed bodyweight of 60 kg
Maximum anticipated dietary exposure: 5 mg/animal/day
Equivalent to: 0.083 mg/kg bw
Equivalent to: 2 ppm in the diet
MFL (Based on the available animal feeding data (Attachment 2): 5 ppm in the diet
Equivalent DDIL: 0.208 mg/kg bw

Pigs

Feed group Feed commodity % in the diet Feed intake, kg/animal/daya MRL, mg/kg % DMb Intake of cyfluthrin, mg/animal/dayc
Processed grain fraction Wheat bran, unprocessed 40 1 5   5
Pulses/ legumes Legume vegetables, pulses 60 1.5 0.5   0.75
Total   100       5.75
aBased on assumed feed consumption of 2.5 kg dry matter/day
bEstimate of percentage dry matter. Applied to MRLs expressed on a fresh weight basis
cBased on assumed bodyweight of 60 kg
Maximum anticipated dietary exposure: 5.75 mg/animal/day
Equivalent to: 0.096 mg/kg bw
Equivalent to: 2.3 ppm in the diet
MFL (Based on the available animal feeding data (Attachment 2): 5 ppm in the diet
Equivalent DDIL: 0.208 mg/kg bw

Poultry

Feed group Feed commodity % in the diet Feed intake, kg/animal/daya MRL, mg/kg % DMb Intake of cyfluthrin, mg/animal/dayc
Processed grain fraction Wheat bran, unprocessed 20 0.03 5   0.15
Pulses/ legumes Legume vegetables, pulses 80 0.12 0.5   0.06
Total   100 0.15     0.21
aBased on assumed feed consumption of 0.150 kg dry matter/day
bEstimate of percentage dry matter. Applied to MRLs expressed on a fresh weight basis
cBased on assumed bodyweight of 2 kg
Maximum anticipated dietary exposure: 0.21 mg/animal/day
Equivalent to: 0.105 mg/kg bw
Equivalent to: 1.4 ppm in the diet
MFL (Based on the available animal feeding data (Attachment 2): 6 ppm in the diet
Equivalent DDIL: 0.26 mg/kg bw

  * at or about the limit of quantitation

See the cyfluthrin anticipated maximum dietary exposure (PDF, 15kb)